產(chǎn)品名稱：BACE 1 ELISA 產(chǎn) 地：Demeditec 產(chǎn)品貨號(hào)：JP27752 產(chǎn)品規(guī)格：96 Tests 產(chǎn)品說(shuō)明： Special remarks: Neuropathologically Alzheimer's disease (AD) is characterized by widespread deposition of amyloid beta protein (Abeta) in the cerebral cortex, and since the intracerebral accumulation of Abeta is highly specific for AD and the gene mutation responsible for familial amyloidosis causes Abeta to increase, Abeta is thought to be of extremely great significance in the pathogenetic mechanism of AD. Abeta is generated by proteolysis of the Abeta precursor protein (APP), a type I membrane protein. The enzyme that cleaves it at the N-terminal is called beta secretase, and it is regarded as being the protease that acts at the initial step in the production of Abeta. The major beta secretase has been identified as beta-site APP Cleaving Enzyme 1 (BACE1), and BACE2 has been isolated as its homologue. Since increased BACE1 activity has also been reported in the brain of patients with sporadic AD, BACE1 inhibitors have been attracting attention as therapeutic agents for AD. The kit can apply to assay of human, mouse and rat BACE1. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國(guó)內(nèi)**地位，公司提供的產(chǎn)品涵蓋了二十多個(gè)國(guó)家近五十萬(wàn)種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長(zhǎng)和更新，公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對(duì)生物化學(xué)，分子生物學(xué)，細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知，以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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