產(chǎn)品名稱(chēng)：Tenascin-C Large (FNIII-C) ELISA 產(chǎn) 地：Demeditec 產(chǎn)品貨號(hào)：JP27751 產(chǎn)品規(guī)格：96 Tests 產(chǎn)品說(shuō)明： Special remarks: This test kit has been developped for the measurement of the Tenascin-C large variant including domain FNIII-C. There is also another testkit available for the measurement of the Tenascin-C large variant including domain FNIII-B (cat.-no. JP27767). Tenascin-C is a modular and multifunctional extracellular matrix (ECM) glycoprotein that is exquisitely regulated during embryonic development and in ***** tissue remodeling. In the ***** organism, reexpression of tenascin-C occurs in tumors and other pathologic conditions. The precise function of the protein remains still unknown. Tenascin-C is a hexameric disulphide-linked protein with subunit molecular weights in the range of 210-400 kD. It is primarily made up of 14.5 epidermal growth-factorlike repeat, 15 units similar to fibronectin type III-homology repeat and, at C-terminus, has a sequence with homology to the globular domain of the b and g chain of fibrinogen. In addition, the amino-terminal -150 amino acids form an oligomerization domain allowing interaction of six subunits. Different subunits are generated by alternative splicing of one common primary transcript. Recent reports have suggested that tenascin-C is upregulated during oncogenesis, arthritis, liver, and lung fibrosis. Increased serum levels have been reported in patients with cancer and liver diseases. The IBL's human Tenascin-C High Molecular Weight Variants Assay kit (L) can detect the non-spliced high molecular weight variants of tenascin-C including domain C in particular. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國(guó)內(nèi)**地位，公司提供的產(chǎn)品涵蓋了二十多個(gè)國(guó)家近五十萬(wàn)種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長(zhǎng)和更新，公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對(duì)生物化學(xué)，分子生物學(xué)，細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知，以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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