產(chǎn)品名稱：Angiopoietin-like 4 human ELISA 產(chǎn) 地：Demeditec 產(chǎn)品貨號：JP27749 產(chǎn)品規(guī)格：96 Tests 產(chǎn)品說明： Special remarks: INTRODUCTION Angiopoetin-like 4 (ANGPTL4) is a member of the angiopoietin/ANGPTL family. Human ANGPTL4 consists of 406 amino acids. Its protein structure is common to the angiopoietins, with a signal peptide directing secretion, an N-terminal coiled-coil domain (CCD), a linker, and a C-terminal fibrinogen-like domain (FLD). Full-length ANGPTL4 is secreted by liver and adipose tissues and cleaved to generate circulating CCD and FLD fragments. ANGPTL4 plays important roles in lipid and glucose metabolism. It inhibits lipoprotein lipase (LPL) activity by breaking the dimmer molecule, and elevates plasma TG level. Meanwhile, it is also implicated in breast cancer metastasis to lung via the regulation of vascular integrity. Both of two antibodies used in this ELISA kit recognize the N-terminal portion of human ANGPTL4 respectively. PRINCIPLE This kit is a solid phase sandwich ELISA using 2 kinds of highly specific antibodies. Tetra Methyl Benzidine (TMB) is used as a coloring agent (Chromogen). The strength of coloring is proportional to the quantities of Human ANGPTL4. INTENDED USE This kit is capable for the quantitative determination human ANGPTL4 in serum and EDTA-plasma. In the case of normal individuals, many of blood samples will fall below the sensitivity. When cell culture media is measured, some suitable arrangements are required (for example, negative media control) since some FBS (FCS) will be measured high level ANGPTL4 with this kit. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國內(nèi)**地位，公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新，公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué)，分子生物學(xué)，細胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認知，以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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