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N-ERC/Mesothelin mouse ELISA

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產(chǎn)品名稱: N-ERC/Mesothelin mouse ELISA
產(chǎn)品型號: JP27783
產(chǎn)品展商: 原裝進(jìn)口
產(chǎn)品文檔: 無相關(guān)文檔

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N-ERC/Mesothelin mouse ELISA


N-ERC/Mesothelin mouse ELISA  的詳細(xì)介紹
N-ERC/Mesothelin mouse ELISA

產(chǎn)品名稱:N-ERC/Mesothelin mouse ELISA
產(chǎn)    地:Demeditec 
產(chǎn)品貨號:JP27783
產(chǎn)品規(guī)格:96 Tests
產(chǎn)品說明:
Special remarks:
INTRODUCTION
Erc has been identified as a gene showing stronger expression in cancer-affected renal tissue than in normal renal tissue in Eker rats (a rat model of renal cancer).
The  human  homologue  of  the  protein  encoded  by  this  gene  is  called  MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in  the  development  of  mesothelioma,  making  it  a promising  tumor  marker.  In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type  membranous  protein (about  71  kDa  in  molecular  weight),  which  is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size.
We think it is helpful for research of ERC/Mesothelin protein and have characterized the 31 kDa fragment as N-ERC/Mesothelin and the 40 kDa fragment as C-ERC/Mesothelin. This ELISA kit can measure Mouse N-ERC/Mesothelin.
PRINCIPLE
This kit is a solid phase sandwich ELISA using 2 kinds of highly specific antibodies. Tetra  Methyl  Benzidine  (TMB)  is  used  as  a  coloring  agent  (Chromogen).  The strength of coloring is proportional to the quantities of Mouse N-ERC/Mesothellin.
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