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Angiotensinogen human

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產(chǎn)品名稱: Angiotensinogen human
產(chǎn)品型號: JP27412
產(chǎn)品展商: 原裝進口
產(chǎn)品文檔: 無相關文檔

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Angiotensinogen human


Angiotensinogen human  的詳細介紹
Angiotensinogen human

產(chǎn)品名稱:Angiotensinogen human
產(chǎn)    地:Demeditec 
產(chǎn)品貨號:JP27412
產(chǎn)品規(guī)格:96 Tests
產(chǎn)品說明:
Special remarks: This testkit has been designed and validated for the measurement of total Angiotensinogen of human origin in various samples.
1 ng Angiotensinogen is equal to 19.23 pMol.
Therefore the measuring range of this assay in molar units is 6 - 384.6 pMol/L.
As serum and plasma samples have to be diluted about 10,000 fold we are supplying separate vials (30 or 100 ml) of additional dilution buffer upon request.
The 30 ml vial is coded 27412D; the 100 ml vial is coded 27412D100.
Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role of the renin-angiotensin system in arterial pressure control and the pathophysiology of hypertension has been shifting to its local role in various tissues. Among the studies urinary excretion of angiotensinogen in a rat model of angiotensin II (AII)-dependent hypertension has been reported to be a marker of the activity of the local intrarenal renin-angiotensin system. Intrarenal AII increases to an extent in AII-dependent hypertension that cannot be explained by the plasma AII equilibration alone, and two mechanisms, an increase in intracellular uptake of AII and an increase in intrarenal expression of angiotensinogen, have been proposed to explain it. This product is a complete kit for the quantitative determination of human angiotensinogen in serum, EDTA-plasma, urine or cell culture media. This assay can be used for clinical testing in patients with high blood pressure or diabetes for example.
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