產(chǎn)品名稱:TSH rat ELISA 產(chǎn) 地:Demeditec 產(chǎn)品貨號:DEV9977 產(chǎn)品規(guī)格:96 Tests 產(chǎn)品說明: Special remarks: Thyroid stimulating hormone (also known as thyrotropin or TSH) is a glycoprotein produced by the anterior pituitary gland. Through its action on the thyroid gland, it plays a major role in maintaining normal circulating levels of the iodothyronines, T4 and T3. The production and secretion of TSH is controlled on the one side by negative feedback from circulating T4 and T3, and on the other side by the hypothalamic thyrotropin-releasing hormone (TRH). The TSH molecule is composed of two non-identical subunits, α and β, that are bound together in a noncovalent manner. Within a species, the TSH α unit is structurally identical to the α subunits of related glycoprotein hormones (LH, FSH). The β subunits of the related hormones are structurally hormone-specific and therefore determine their unique biological activities. The mechanism controlling thyroid function in rats is exactly analogous to the mechanism operating in humans. This means that thyrotropin-releasing hormone stimulates the release of TSH from the pituitary gland as well as the serum concentrations of T4 and T3 influence the action of the pituitary gland. This similarity between rat and human thyroid physiology makes the rat a very useful model for evaluating the effects of new drugs on thyrometabolic status. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國內(nèi)**地位,公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué),分子生物學(xué),細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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