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Androstenedione free in saliva

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產(chǎn)品名稱: Androstenedione free in saliva
產(chǎn)品型號(hào): DESLV4780
產(chǎn)品展商: 原裝進(jìn)口
產(chǎn)品文檔: 無(wú)相關(guān)文檔

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Androstenedione free in saliva


Androstenedione free in saliva  的詳細(xì)介紹
Androstenedione free in saliva

產(chǎn)品名稱:Androstenedione free in saliva
產(chǎn)    地:Demeditec 
產(chǎn)品貨號(hào):DESLV4780
產(chǎn)品規(guī)格:96 Tests
產(chǎn)品說(shuō)明:
Special remarks: In order to avoid arbitrary results we highly are recommending to always take 5 samples during a 2 hour period preferably directly after waking up. Later the laboratory will measure the average value of the mixture.
Appropriate saliva collection sets are available from Demeditec. Special sampling devices for newborns or handicapped patients also are available from Demeditec upon request. These are small soft plastic Pasteur pipettes. Please contact us for further details.
Androstenedione (also known as 4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol. It is the common precursor of male and female sex hormones. Some androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.
Androstenedione originates either from the conversion of dehydroepiandrosterone or from 17-hydroxyprogesterone. It is further converted to either testosterone or estrone.
The production of adrenal androstenedione is governed by ACTH, while production of gonadal androstenedione is under control by gonadotropins. In premenopausal women the adrenal glands and ovaries each produce about half of the total androstendione (about 3 mg/day). After menopause androstenedione production is about halved, primarily due to the reduction of steroid secreted by the ovary. Nevertheless, androstenedione is the principal steroid produced by the postmenopausal ovary.
Increased Androstenedione levels often are seen in PCOS.
Androstenedione as a supplement
Androstenedione is manufactured as dietary supplement, often called andro for short. The supplement is banned by the World Anti-Doping Agency, and hence from the Olympic Games.
On April 11, 2004, the United States Food and Drug Administration banned the sale of Andro, citing that the drug poses significant health risks commonly associated with steroids.
Because androstenedione is converted in part to estrogens, persons taking this supplement may have estrogenic side effects. A visible problem could be gynecomastia (formation of breast tissue) in males.
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