產(chǎn)品名稱(chēng):EBV (EBNA-1) IgG ELISA 產(chǎn) 地:Demeditec 產(chǎn)品貨號(hào):DEEBN01 產(chǎn)品規(guī)格:96 Tests 其它產(chǎn)品: EBV (EBNA-1) IgA Demeditec DEEBN02 96 Tests 1628 EBV (EBNA-1) IgM Demeditec DEEBN03 96 Tests 1628 產(chǎn)品說(shuō)明: Special remarks: The DEMEDITEC EBV EBNA-1 IgG Antibody ELISA Test Kit has been designed for the the detection and the quantitative determination of specific IgG antibodies against EBV EBNA-1 in serum and plasma. The antigen used for coating the plöates is a recombinant one (sf-9, baculovirus). In 1961 an infectious disease was identified in Uganda, which was correlated with the appearance of a defined type of tumor with children. The illness, which is found predominantly in Africa and Papua-New Guinea, was named Burkitt lymphoma from its discoverer. The Epstein Barr virus is made responsible for a variety of diseases like infectious mononucleosis, Burkitt lymphoma, as well as nasopharyngeal carcinoma. In addition, a role of the virus is discussed in connection with Hodgkin´s disease. Especially with teenagers there appears a glandular fever syndrome, which is called „kissing disease“. Diseases which are caused by the Epstein Barr virus are found mainly in persons with reduced immunity. For example, the virus is associated with a lymphoproliferative disease which occurs after transplantation. The immune system of such patients is usually impaired by drug therapy. Also in immune-deficient AIDS patients, there appears frequently a state where cells at the rim of the tongue are infected (oral hairy leukoplakia). Infected persons keep the Epstein-Barr virus forever in their body, they are however mostly not ill. In the developing countries practically all the people are infected, in the western world the incidence is between 80% and 90%. The transmittance occurs already during childhood, perhaps by transfer from the mother, mainly via the saliva. During the active phase of the viral cycle, the Epstein-Barr virus produces about 100 different antigens, in the inactive phase around 10. The latter comprises among others the EBV nuclear antigen EBNA-1, which is closely correlated with a past infection and an immunity. The early antigen (EA) as well as the virus capsid antigen (VCA) from the active phase are also used as diagnostic markers. In a fresh infection, IgM antibodies against VCA and EA are determined by immunofluorescence or ELISA. Later VCA IgG and afterwards EBNA-1 IgG antibodies appear. The simultaneous activation of VCA IgM and EBNA-1 IgG indicates correspondingly a reactivation of a latent EBV infection. The Demeditec EBNA-1 IgG ELISA monitors a past infection satisfactorily and can be utilized for the assessment of blood samples before transfusions or transplantations and the exclusion of transmittance between children. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國(guó)內(nèi)**地位,公司提供的產(chǎn)品涵蓋了二十多個(gè)國(guó)家近五十萬(wàn)種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長(zhǎng)和更新,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對(duì)生物化學(xué),分子生物學(xué),細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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