產(chǎn)品名稱：Thyroglobuline (hTG) ELISA 產(chǎn) 地：Demeditec 產(chǎn)品貨號：DE7680 產(chǎn)品規(guī)格：96 Tests 產(chǎn)品說明： Special remarks: Thyroglobulin is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of thyroglobulin in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of various thyroid diseases such as thyroiditis and hyperthyroidism. Thyroglobulin (hTG) is a multiple glycosylated, water soluble iodoprotein. The molecular weight of approx. 660.000 Dalton is shared by two identical subunits. Thyroglobulin is synthesized in the thyrocytes of the thyroid gland and secreted into the lumen of the thyroid follicles. Iodination of the protein’s tyrosyl residues generates the precursors of the thyroid hormones T3 and T4. Finally the free T3 and free T4 are liberated into circulation, together with small amounts of thyroglobulin. Like for T3 and T4, synthesis and secretion of thyroglobulin is controlled by TSH and TRH. Suppressive medication using the thyroid hormones also leads to lower thyroglobulin serum concentration. Elevated thyroglobulin serum concentrations have been reported in various thyroid diseases, such as - hyperthyroiditis - non-toxic goitre - thyroiditis - differentiated thyroid carcinoma Determination of thyroglobulin is a special prognostic value in Graves’ disease patients undergoing therapy. Highly elevated hTG values at the end of a thyrostatic therapy are indicative for an early recidivation, whereas for patients with continuous low thyroglobulin concentrations prognosis tends to continual recovery. A main application for the thyroglobulin determination is the post surgical monitoring of patients with differentiated thyroid carcinoma. After thyroidectomy, combined with x-ray therapy to destroy remaining thyroid tissue, one can expect an intermediate peak followed by a fast decrease of circulating thyroglobulin concentrations below the detection limit. Each renewed increase of serum thyroglobulin is indicative for residual thyroid tissue, a local recidivation of metastases. Due to its easy repeatability in the routine monitoring of thyroid carcinoma patients, the determination of thyroglobulin is a valuable non-invasive alternative and supplement to 131I-scintigraphy 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國內(nèi)**地位，公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新，公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué)，分子生物學(xué)，細胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認知，以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
滬公網(wǎng)安備 31011002002623號
