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SHBG IRMA

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產(chǎn)品名稱: SHBG IRMA
產(chǎn)品型號(hào): DE46100
產(chǎn)品展商: 原裝進(jìn)口
產(chǎn)品文檔: 無(wú)相關(guān)文檔

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SHBG IRMA


SHBG IRMA  的詳細(xì)介紹
SHBG IRMA

產(chǎn)品名稱:SHBG IRMA
產(chǎn)    地:Demeditec 
產(chǎn)品貨號(hào):DE46100
產(chǎn)品規(guī)格:100 Tests
產(chǎn)品說(shuō)明:
Special remarks:
Sex hormone-binding globulin (SHBG), also known as Testosterone-estradiol binding globulin (TEBG) and sex steroid binding protein (SBP), is a circulating glycoprotein with a molecular weight of around 86000. It is thought to be synthesized in the liver, and in the circulation its biological function is the transport of sex steroid hormones.It has a high binding affinity for testosterone, dihydrotestosterone and estradiol. Serum SHBG levels are relatively low at birth, increase to high levels during infancy, then decrease during puberty. The highest physiologic levels of SHBG are observed in pregnant, near-term maternal serum. Abnormal serum SHBG levels have been reported in number of conditions, including obesity and female hyperandrogenism (including polycystic ovary dicease). Serum SHBG levels are inversely related to free, presumably bioactive, testosterone concentracions, a “free testosterone index” based on the ratio of total testosterone to SHBG has been characterized.
In general the measurement of SHBG offers the possibility for calculating the free fraction of vatious steroid hormones based on the measurement of the total concentration in serum. But there is also a method available for the direct measurement of free steroid hormones in saliva. The metabolic activity of any steroid in any case is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering a group of different testkits in ELISA format for the measurement of free steroid hormones in saliva (please check in the chapter "saliva testing").
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