產(chǎn)品名稱:SHBG IRMA 產(chǎn) 地:Demeditec 產(chǎn)品貨號(hào):DE46100 產(chǎn)品規(guī)格:100 Tests 產(chǎn)品說(shuō)明: Special remarks: Sex hormone-binding globulin (SHBG), also known as Testosterone-estradiol binding globulin (TEBG) and sex steroid binding protein (SBP), is a circulating glycoprotein with a molecular weight of around 86000. It is thought to be synthesized in the liver, and in the circulation its biological function is the transport of sex steroid hormones.It has a high binding affinity for testosterone, dihydrotestosterone and estradiol. Serum SHBG levels are relatively low at birth, increase to high levels during infancy, then decrease during puberty. The highest physiologic levels of SHBG are observed in pregnant, near-term maternal serum. Abnormal serum SHBG levels have been reported in number of conditions, including obesity and female hyperandrogenism (including polycystic ovary dicease). Serum SHBG levels are inversely related to free, presumably bioactive, testosterone concentracions, a “free testosterone index” based on the ratio of total testosterone to SHBG has been characterized. In general the measurement of SHBG offers the possibility for calculating the free fraction of vatious steroid hormones based on the measurement of the total concentration in serum. But there is also a method available for the direct measurement of free steroid hormones in saliva. The metabolic activity of any steroid in any case is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering a group of different testkits in ELISA format for the measurement of free steroid hormones in saliva (please check in the chapter "saliva testing"). 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國(guó)內(nèi)**地位,公司提供的產(chǎn)品涵蓋了二十多個(gè)國(guó)家近五十萬(wàn)種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長(zhǎng)和更新,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對(duì)生物化學(xué),分子生物學(xué),細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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