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產(chǎn)品資料

delta-4-Androstenedione RIA

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產(chǎn)品名稱: delta-4-Androstenedione RIA
產(chǎn)品型號: DE4388
產(chǎn)品展商: 原裝進口
產(chǎn)品文檔: 無相關文檔

簡單介紹

delta-4-Androstenedione RIA


delta-4-Androstenedione RIA  的詳細介紹
delta-4-Androstenedione RIA

產(chǎn)品名稱:delta-4-Androstenedione RIA
產(chǎn)    地:Demeditec
產(chǎn)品貨號:DE4388
產(chǎn)品規(guī)格:96 Tests
產(chǎn)品說明:
Special remarks:
The steroid hormone Androstenedione is one of the main androgens, besides Testosterone and Dehydroepiandrosterone. Testosterone, the most important biological active androgen, is derived from peripheral enzymatic conversion of Androstenedione.
In males, androgens are secreted primarily by the Leydig cells of the testes, to some degree also in the adrenal cortex. In females, the androgens are secreted mainly in the adrenal glands and in the ovary. Around 10% of the androgens are derived from peripheral conversion, mainly of DHEA. Androstenedione and Testosterone show high diurnal variability. The highest levels are measured in the morning. At the age of puberty serum androstenedione levels rise, after menopause they decline again. High androstenedione levels are measured during pregnancy. In women, high levels of androstenedione (47-100% above normal) are generally found in hirsutism, mostly in combination with other androgens as testosterone and DHEA-S. Androstenedione overproduction is due to ovarian dysfunction or maybe of adrenal origin. High circulating androstenedione levels are found in women with polycystic ovaries and 21-hydroxylase effect. Significant lower androstenedione levels are found in postmenopausal osteoporosis.
There is also a method available for the measurement of free Androstenendione in saliva. The metabolic activity of any steroid is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number DESLV4780 (please check in the chapter "saliva testing".
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