產(chǎn)品名稱：Prolactin IRMA 產(chǎn) 地：Demeditec 產(chǎn)品貨號：DE32100 產(chǎn)品規(guī)格：100 Tests 產(chǎn)品說明： Special remarks: Introduction Prolactin (hPRL) is a protein hormone with a molecular weight of 22000, secreted by the pituitary gland. The hPRL synthesis and release are believed to be controlled by the Prolactin Releasing Factor although the identity of this is uncertain. TRH has been shown to stimulate the release of prolactin too. Prolactin release is under inhibitory control by the prolactin-inhibiting factor (PIF). Hyperprolactinemia is a common cause of gonadal dysfunction in women and men, but there are numerous physiological and pathological conditions resulted in hyperprolactinemia. Principle of method The technology uses two high affinity monoclonal antibodies in an immunoradiometric assay (IRMA) system. The 125I labelled signal-antibody binds to an epitope of the PRL molecule spatially different from that recognized by the biotin-capture-antibody. The two antibodies react simultaneously with the antigen present in standards or samples, which leads to the formation of a capture antibody - antigen - signal antibody complex, also referred to as a “sandwich”. During a 2-hour incubation period with shaking immuno-complex is immobilized to the reactive surface of streptavidin coated test tubes. Reaction mixture is then discarded, test tubes washed exhaustively, and the radioactivity is measured in a gamma counter. The concentration of antigen is directly proportional to the radioactivity measured in test tubes. By constructing a calibration curve plotting binding values against a series of calibrators containing known amount of hPRL, the unknown concentration of hPRL in patient samples can determined 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國內(nèi)**地位，公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新，公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué)，分子生物學(xué)，細胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知，以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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