產(chǎn)品名稱:Ferritin IRMA 產(chǎn) 地:Demeditec 產(chǎn)品貨號(hào):DE34100 產(chǎn)品規(guī)格:100 Tests 產(chǎn)品說明: Special remarks: Introduction Ferritin is the main storage protein for iron (Mw:450000) containing protein shell and a crystalline core iron oxide and phosphate. Low serum ferritin level is a useful diagnostic marker for iron-deficiency anemia. High ferritin levels may indicate iron overload in the case of hemochromatosis. Elevated serum ferritin levels may also be observed in acute and chronic liver disease. Principle of method The technology uses two high affinity monoclonal antibodies in an immuno-radiometric assay (IRMA) system. The 125I labelled signal-antibody binds to an epitope of the ferritin molecule, which is different from that recognised by the unlabelled capture-antibody. The two antibodies react simultaneously with the antigen present in standards or samples which leads to the formation of a capture antibody - antigen - signal antibody complex, also referred to as a “sandwich”. During a 2-hours incubation period with continuous agitation immuno-complex is immobilized on the reactive surface of test tubes. Reaction mixture is then discarded, test tubes are washed exhaustively, and the radioactivity is measured in a gamma counter. The concentration of antigen is directly proportional to the radioactivity measured in test tubes. By constructing a calibration curve plotting binding values against a series of standards containing known amount of ferritin, the unknown concentration of ferritin in patient samples can be determined. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于國(guó)內(nèi)**地位,公司提供的產(chǎn)品涵蓋了二十多個(gè)國(guó)家近五十萬(wàn)種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長(zhǎng)和更新,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對(duì)生物化學(xué),分子生物學(xué),細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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