產品名稱：hPL ELISA
產    地：Demeditec 
產品貨號：DE1283
產品規(guī)格：96 Tests
產品說明：
1 Introduction
The DEMEDITEC hPL Enzyme Immunoassay Kit provides materials for the quantitative determination of human Placental Lactogen (hPL) in serum.
This assay is intended for in vitro diagnostic use only.
The physiological role of HPL has not yet been established, but the great similarity to human growth hormone has stimulated the hypothesis about a function as a regulator of feto-placental growth and other physiological alterations during pregnancy. It has been suggested that the maternal serum-level may reflect on "index of placental function".
Depressed levels of HPL are seen in association with intrauterine death, fetal distress in labor and birth asphyxia. This association is particularly strong if depressed levels are seen repeatedly, implying a chronic state of placental and therefore fetal compromise. Depressed levels are usually not present if the pregnancy has proceeded uneventfully to term.
Elevated levels of HPL are usually indicative of optimal pregnancy outcome in singleton pregnancies. However, high levels may indicate substantial fetal pathology in specific diseases, namely diabetes mellitus and fetal macrosomia, rhesus isoimmunization and hydrops fetalis.
2 Principle of the test
The DEMEDITEC hPL ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle.
The microtiter wells are coated with a monoclonal antibody directed towards a unique antigenic site on an hPL molecule.  An aliquot of patient sample containing endogenous hPL is incubated in the coated well with enzyme conjugate, which is an monoclonal anti-hPL antibody conjugated with horseradish peroxidase. After incubation the unbound conjugate is washed off.
The amount of bound peroxidase is proportional to the concentration of hPL in the sample.
Having added the substrate solution, the intensity of colour developed is proportional to the concentration of hPL in the patient sample.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于國內**地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫(yī)學領域的應用。

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