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產(chǎn)品資料

CD23

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產(chǎn)品名稱: CD23
產(chǎn)品型號: IQP-154P
產(chǎn)品展商: 原裝進(jìn)口
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

CD23


CD23  的詳細(xì)介紹
CD23

產(chǎn)品名稱:CD23
產(chǎn)    地:IQ Products
產(chǎn)品貨號:IQP-154P
產(chǎn)品規(guī)格:1.0 mL for 100 test
其它產(chǎn)品:
CD23 IQ Products IQP-154R 1.0 mL for 100 test 4910
產(chǎn)品說明:
B-G6 antigen is a low affinity receptor for IgE (FceR) and both the FceRIIa and FceRIIb are expressed on mature IgD+/IgM+ B cells. The FceRIIb form is also present on monocytes, activated macrophages, eosinophils, platelets and follicular dendritic cells. CD23 is also present in a soluble form in serum. CD23 together with CD19 and CD22, plays a role in the modulation of B cell activation through membrane immunoglobulin and is involved in regulation of IgE synthesis. Expression of CD23 is increased by IL-4 and down-regulated by B-cell growth factor (BCGF). Binding of IgE immune complexes to CD23 increases the efficiency of B cell antigen processing and presentation. Via its interaction with CD21 it may play a role in adhesion processes. It mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils.
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