產(chǎn)品名稱：17-AAG 規(guī)格：25 mg 貨號(hào)：ant-agl-25 廠商：invivogen 產(chǎn)品介紹: Working concentration: 10 nM - 10 μM CAS number: 75747-14-7 Formula: C31H43N3O8 Molecular weight: 586 Solubility: Soluble in DMSO (10 mg/ml) 17-Allylamino-17-demethoxygeldanamycin- An Hsp90 inhibitor 17-Allylamino-17-demethoxygeldanamycin (17AAG) is a less toxic and more stable analog of geldanamycin (GA) [1]. Even though 17-AAG binding to Hsp90 is weaker than GA,17-AAG displays similar antitumor effects as GA and a better toxicity profile. 17-AAG is currently in phase I clinical trial in several centers worldwide. Preliminary data obtained from these trials demonstrate that antitumor activity is achieved at concentrations below the maximum tolerated dose [2]. invivogen ant-agl-25 17-AAG 25 mg 5264 invivogen ant-agl-5 17-AAG 5 mg 1806
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