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產品名稱：Y27632 產品貨號：Affix AF3046 產品規(guī)格：10 mg Technical Data Chemical Name 4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride Biological Description Y-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. Activation of excitatory receptors coupled to G-proteins can cause contraction of smooth muscle by increasing Ca2+-sensitivity without changing [Ca2+]. This pathway involves RhoA, a small, monomeric G-protein that activates Rho-kinase. Molecular Weight 320.26 daltons Molecular Formula C14H21N3O.2HCI Solubility Soluble to 100 mM in water Purity >98% Storage instructions Up to one week at 4°C or six months at -20°C. CAS No. 146986-50-7 References
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