產(chǎn)品名稱：Amlodipine Besylate 產(chǎn)品貨號：Affix AF3010 產(chǎn)品規(guī)格：50 mg Technical Data Chemical Name 2-[(2-Aminoethoxy)methyl]-4-(2-chlo rophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarbo xylic acid 3-ethyl 5-methyl ester benzenesulfonate Biological Description Amlodipine besylate is a L-type (CaV1), voltage-gated Ca2+ channels.Amlodipine besylate is a DHP that acts as L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat hypertension. It inhibited Ca2+ -induced contractions in depolarised rat aorta (IC50 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Molecular Weight 567.1 daltons Molecular Formula C20H25ClN2O5*C6H6O3S Solubility Soluble to 10 mM in water and to 100 mM in DMSO Purity >99 % Storage instructions Store at RT CAS No. 111470-99-6 References Julius, S. et al. (2004) The Lancet 363, 2022.
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