產(chǎn)品名稱：Cyclopiazonic Acid 產(chǎn)品貨號(hào)：Affix AF3005 產(chǎn)品規(guī)格：10 MG Technical Data Chemical Name：(6aR,11aS,11bR)-rel-10-Acetyl-2,6,6a,7,11a,11b-hexahydr o-7,7-dimethyl-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd] indol-9-one. Biological Description：Cyclopiazonic Acid is a Cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase.Cyclopiazonic Acid is a highly specific inhibitor of the Ca2+-ATPase of sarcoplasmic reticulum, completely inhibiting the enzyme at 6-8 nmol/mg protein at the low concentration of 0.5-2 µM. The use of Cyclopiazonic acid on Langendorff-perfused murine hearts displayed anti-arrhythmic effects. Molecular Weight 336.39 Molecular Formula C20H20N2O3 Solubility Soluble in ethanol (5 mM) and in DMSO (100 mM) Purity >98 % Storage instructions Store at -20°C CAS No. 18172-33-3 References Demaurex, N. et al. (1992) J. Biol. Chem. 267, 2318.
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