產(chǎn)品名稱:Ingenol 3-Angelate 產(chǎn)品貨號(hào):LC I-5900 產(chǎn)品規(guī)格:5 MG Protein Kinase C activator; anti-cancer drug. Hampson, P., et al. "PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC." Blood 106: 1362-1368 (2005). Kedei, N., et al. "Characterization of the interaction of ingenol 3-angelate with protein kinase C." Cancer Res. 64: 3243-3255 (2004). Treatment with acids or bases or heating may cause rearrangement of the angeloyl group to the 5- or 20-positions leading to a significant decrease in potency. SPECIAL HAZARD: TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure. Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO or ethanol. Disposal: A
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