產(chǎn)品名稱：Wortmannin 產(chǎn)品貨號：LTK W5769 產(chǎn)品規(guī)格：1 MG Description Is an inhibitor of PI3-K and DNa-dependent protein kinase, which is known to mediate DNA double strand break repair. It induces apoptosis and also sensitize cells to ionizing radiation. Specifications Cas No. 19545-26-7 Product ID W5769 Product Name Wortmannin Chemical Name (1S,6bR,9aS,11R,11bR)-11-(Acetyloxy)-1,6b,7,8,9a,10,-11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]ideno[4,5-h]-2-benzopyran-3,6,9- trione Synonym Wartmannin Formula Wt. 428.43 Melting Point 240oC Purity ≥98% Solubility Soluble in methanol and DMSO. Stability Unstable in aqueous solutions of pH 3-8. Dessicate. Store Temp -20oC Ship Temp Ambient References Boulton S, Kyle S, Yalcintepe L, Durkacz BW. Carcinogenesis. 17 : 2285 -90 (1996). Ng SSW, Tsao MS, Chow S, Hedley DW. Cancer Res. 60: 5451-5 (2000). Kubota N, Okada S, Inada T, Ohnishi K, Ohnishi T. Cancer Lett. 161:141-7 (2000).
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