產(chǎn)品名稱：Geldanamycin 產(chǎn)品貨號：LKT G1646 產(chǎn)品規(guī)格：1mg Description A benzoquinoid ansamycin antibiotic having antitumor activities. It suppresses DNA replication by inhibiting c-myc gene expression in lymphoblastoma L5178Y cells. It inhibits tyrosine kinases and induces increased p53 protein involved in cell-cycle arrests of human ovarian tumor cells. It inhibits the 90 kDa heat shock protein that reglates cell signal transduction, and telomerase activity, and induces apoptosis. Specifications Cas No. 30562-34-6 Product ID G1646 Product Name Geldanamycin Synonym BRN 1633093 Formula Wt. 560.64 Melting Point 265 Purity ≥97% Solubility Soluble in DMSO. Stability Protect from light. Store Temp -20oC References Yamaki H, Iguchi-Ariga SM, Ariga H. J Antibiot (Tokyo). 42:604-10 (1989). McIlwrath AJ, Brunton VG, Brown R. Cancer Chemother Pharmacol. 37:423-8 (1996). Villa R, Folini M, Porta CD et al. Carcinogenesis. 24:851-9 (2003). Kim S, Kang J, Hu W. Int J Can
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