Brevetoxin 3 42-Acetate (PbTx-3 Acetate) **
產(chǎn)品名稱：Brevetoxin 3 42-Acetate (PbTx-3 Acetate)
產(chǎn)品貨號：LKT B6919
產(chǎn)品規(guī)格：100µg
Description
Brevetoxins are known to bind to site 5 of voltage-gated sodium channels in nerve cells, leading to channel activation. This leads to disruption of normal neurological processes and causes the illness clinically described as neurotoxic shellfish poisoning (NSP).1 PbTx-OAc acetate contains a brevetoxin B backbone. This brevetoxin derivative does not occur in nature and is used as an internal recovery standard in quantitative analytical procedures involving determination of Brevetoxins.2
Specifications
Cas No. 1039726-95-8
Product ID B6919
Product Name Brevetoxin 3 42-Acetate (PbTx-3 Acetate)
Synonym PbTx-OAc, PbTx-3 42-Acetate
Formula Wt. 939.13
References 1 (a) Edwards, R. A. et al. Mol. Brain Res. (1992) 14, 64-70; (b) Trainer, V. L. et al. Mol. Pharmacol. (1991) 40, 988-994; (c) Tsai, M. C., and Chen, M. L. Br. J. Pharmacol. (1991) 103, 1126-1128; (d) Trainer, V. L. et al. ACS Symposium Series (1990) 418, 166; (e) Baden, D. G. FASEB J. (1989) 3, 1807-1817; (f) Baden, D. G. et al. Toxicon (1988) 26, 97-103; (g) Poli, M. A. et al. Mol. Pharmacol. (1986) 30, 129-135; (h) Shimizu, Y. et al. J. Am. Chem. Soc. (1986) 108, 514-515; (i) Nakanishi, K. Toxicon (1985) 23, 473-479; (j) Baden, D. G. et al. Toxicon (1982) 19, 455-462; (k) Catterfall, W. A., and Risk, M. Mol. Pharmacol. (1981) 19, 345-348. 2 Errera,, R. M., Bourdelais, A., Drennan, M. A., Dodd, E. B., Henrichs, D. W., and Campbell, L., Toxicon 55 (2010) 195-203
