產(chǎn)品名稱：GSK3b (Total) InstantOne™ ELISA 產(chǎn)品貨號：eBioscience 85-86171-11 產(chǎn)品規(guī)格：96 tests GSK3 beta (Total) InstantOne™ ELISA Also known as: Glycogen synthase kinase-3 beta RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 85-86171 Cat. No. Size 85-86171-11 96 tests Description: The InstantOne™ ELISA is specifically engineered for accurate measurement of total human and mouse GSK3b in cell lysates. Detection of rat GSK3b is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate. Glycogen Synthase Kinase 3 (GSK3) is a Ser/Thr kinase that exists as two isoforms, GSK3a and GSK3b. Unlike other kinases, phosphorylation at Ser9 and Ser21 for GSK3a and GSK3b, respectively, leads to inactivation of this enzyme. GSK3 has been implicated in several diseases, including cancer and diabetes, through its phosphorylation of glycogen synthase. GSK3 has also been associated with neurodegenerative diseases such as Alzheimer's disease due to its phosphorylation of the neuronal Tau protein.
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