CD22 PerCP-eFluor 710 s-HCL-1, ASR, **
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產(chǎn)品名稱: CD22 PerCP-eFluor 710 s-HCL-1, ASR, **
產(chǎn)品型號: 8046-4229-120
產(chǎn)品展商: 原裝進(jìn)口
產(chǎn)品文檔: 無相關(guān)文檔
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CD22 PerCP-eFluor 710 s-HCL-1, ASR, **
CD22 PerCP-eFluor 710 s-HCL-1, ASR, **
的詳細(xì)介紹
CD22 PerCP-eFluor 710 s-HCL-1, ASR, **
產(chǎn)品名稱：CD22 PerCP-eFluor 710 s-HCL-1, ASR, 120 tests
產(chǎn)品貨號：eBioscience 8046-4229-120
產(chǎn)品規(guī)格：120 tests
CD22 PerCP-eFluor® 710
Also known as: Siglec-2
Clone: S-HCL-1
Analyte Specific Reagent (ASR): Analytical and performance characteristics are not established.
SKU# 8046-4229
Cat. No. Size
8046-4229-025 25 tests
8046-4229-120 120 tests
Description: The S-HCl-1 monoclonal antibody recognizes human CD22 (Siglec-2), which is a member of the siglec subgroup of the Ig superfamily. CD22 is a type I transmembrane glycoprotein composed of two polypeptide chains, CD22 alpha and CD22 beta, 130 and 140 kDa respectively, produced by alternative splicing of the CD22 gene. CD22 is expressed at high levels on mature B cells. The extracellular portion of CD22 contains seven Ig-like domains, some of which are capable of binding ligands with sialic acid moieties expressed on epithelial, endothelial, B and T cells. The intracellular portion of CD22 contains 6 tyrosine residues contained within immunotyrosine-based inhibitory motifs (ITIM) and immunotyrosine-based activation-like motifs (ITAM), which are phosphorylated upon B-cell receptor engagement and enable CD22 to participate in the positive and negative regulation of B-cell receptor signaling.
