產(chǎn)品名稱：Mouse Granzyme B ELISA Ready-SET-Go! Set 2 plates (includes plates) 產(chǎn)品貨號：eBioscience 88-8022-22 產(chǎn)品規(guī)格：2 x 96 tests Mouse Granzyme B ELISA Ready-SET-Go!® Also known as: GrzB, GzB RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 88-8022 Cat. No. Size 88-8022-22 2 x 96 tests w/plates 88-8022-86 10 x 96 tests w/plates 88-8022-88 10 x 96 tests Description: One of the major mechanisms of cell-mediated cytotoxicity involves exocytosis of cytoplasmic granules from the effector cell toward the target cell. The granules contain a number of proteins, including the pore-forming protein perforin and a family of serine proteases called granzymes, including Granzyme B. Granzyme B is present mainly in the granules of CD8+ CTL and natural killer (NK) cells and mediates the lethal hit that kills virus infected and tumorigenic cells. Measurement of release of Granzyme B in response to the appropriate target is useful for evaluating cell-mediated cytotoxicity.
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