產(chǎn)品名稱(chēng)：anti-mouse F4/80 Antigen Alexa Fluor® 488 BM8 100 ug 產(chǎn)品貨號(hào)：eBioscience 53-4801-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse F4/80 Antigen Alexa Fluor® 488 Also known as: F480, Pan Macrophage Marker Clone: BM8 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 53-4801 Cat. No. Size 53-4801-80 25 ug 53-4801-82 100 ug Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated \i{in vitro\i} with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment \i{in vivo\i}.
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