產(chǎn)品名稱：anti-mouse CD25 Alexa Fluor® 488 eBio3C7 (3C7) 100 ug 產(chǎn)品貨號：eBioscience 53-0253-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse CD25 Alexa Fluor® 488 Also known as: Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra, Tac, Ly-43 Clone: eBio3C7 (3C7) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 53-0253 Cat. No. Size 53-0253-80 25 ug 53-0253-82 100 ug Description: The eBio3C7 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) and subsequent detection with another CD25 antibody.
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