產(chǎn)品名稱：Anti-Mouse TIGIT Alexa Fluor® 647 (GIGD7) 100 ug 產(chǎn)品貨號：eBioscience 51-9501-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse TIGIT Alexa Fluor® 647 Also known as: VSTM3, WUCAM Clone: GIGD7 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 51-9501 Cat. No. Size 51-9501-80 25 ug 51-9501-82 100 ug Description: The GIGD7 monoclonal antibody reacts with mouse T cell immunoreceptor with Ig and ITIM domains (TIGIT, VSTM3, WUCAM), a 26 kDa protein that is a member of the poliovirus receptor (PVR) family. In mice, the expression of TIGIT has been reported in follicular T helper cells, while in humans, the expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells. TIGIT is not expressed on B cells or naïve CD4+ T cells. TIGIT is upregulated on CD4+ T cells following activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK cells and T cells with antigen presenting cells, fibroblasts and endothelial cells that express PVR and PVR-like proteins.
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