產(chǎn)品名稱:anti-human IL-9 Alexa Fluor® 647 MH9A4 100 tests 產(chǎn)品貨號(hào):eBioscience 51-7097-73 產(chǎn)品規(guī)格:100 tests Anti-Human IL-9 Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format eFluor® 660, cat. 50-7097) Also known as: Interleukin-9, IL9 Clone: MH9A4 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 51-7097 Cat. No. Size 51-7097-71 25 tests 51-7097-73 100 tests Description: The monoclonal antibody MH9A4 recognizes interleukin-9 (IL-9), a proinflammatory cytokine historically believed to be involved in type 2 immune responses. Recent evidence suggests IL-9 may instead be secreted by a distinct T-helper lineage called Th9. These cells can be derived from Th2 cells with TGF beta or differentiated directly from naïve CD4+ T cells with TGF beta and IL-4. IL-9 is a member of the common cytokine receptor gamma chain-dependent family of cytokines which also includes IL-2, IL-4, IL-7, IL-15 and IL-21. Its pleiotropic effects on Th2 lymphocytes, B lymphocytes, mast cells, eosinophils and gut and airway epithelial cells have implicated IL-9 in asthma and other allergy-related disorders. Staining with the MH9A4 antibody is not blocked by the MH9D1 antibody, suggesting that the two antibodies bind to unique epitopes.
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