產(chǎn)品名稱(chēng):anti-mouse CD127 Alexa Fluor® 647 A7R34 100 ug 產(chǎn)品貨號(hào):eBioscience 51-1271-82 產(chǎn)品規(guī)格:100 ug Anti-Mouse CD127 Alexa Fluor® 647 (To Be Discontinued. Refer to Cat. No. 50-1271) Also known as: 'Interleukin-7 Receptor alpha, IL-7Ra Clone: A7R34 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 51-1271 Cat. No. Size 51-1271-80 25 ug 51-1271-82 100 ug Description: The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity α subunit of the mouse IL-7 receptor. IL-7 receptor α chain is expressed by immature B cells in the bone marrow, double-negative (CD4-/CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+/CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.
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