產(chǎn)品名稱：eFluor 660 Human CD36 (clone NL07), 100 tests 產(chǎn)品貨號：eBioscience 50-0341-82 產(chǎn)品規(guī)格：100 tests Anti-Human CD36 eFluor® 660 (Alexa Fluor® 647 Replacement) Also known as: Platelet glycoprotein 4 Clone: eBioNL07 (NL07) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 50-0369 Cat. No. Size 50-0369-41 25 tests 50-0369-42 100 tests Description: The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Nak-a negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to “minimally” oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.
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