產品名稱：Mouse TLR2 (clone T2.5), 100 ug 產品貨號：eBioscience 48-9024-82 產品規(guī)格：100 ug Anti-Human/Mouse CD282 (TLR2) eFluor® 450 Also known as: TLR-2, toll-like receptor 2 Clone: T2.5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 48-9024 Cat. No. Size 48-9024-80 25 ug 48-9024-82 100 ug Description: The T2.5 monoclonal antibody reacts with mouse and human Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens. T2.5 is an antagonistic antibody.
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