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產(chǎn)品名稱:Anti-Human CD161 (clone HP-3G10) eFluor® 450, 100 tests
產(chǎn)品貨號(hào):eBioscience 48-1619-42
產(chǎn)品規(guī)格:100 tests
Anti-Human CD161 eFluor® 450
Also known as: NKRP1A
Clone: HP-3G10
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 48-1619
Cat. No. Size
48-1619-41 25 tests
48-1619-42 100 tests
Description: This HP-3G10 monoclonal antibody reacts with CD161 (also known as NKR-P1A), a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gamma delta TCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 (LLT1), which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161.