Allophycocyanin-eFluor? 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: Allophycocyanin-eFluor? 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-
產(chǎn)品型號(hào): 47-1979-42
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Allophycocyanin-eFluor? 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-Alexa Fluor® 750 repl
Allophycocyanin-eFluor? 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-
的詳細(xì)介紹
Allophycocyanin-eFluor? 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-Alexa Fluor® 750 repl
產(chǎn)品名稱：Allophycocyanin-eFluor™ 780 anti-human CCR7 (CD197, BLR-2, EBI-1, CMKBR7) (APC-Alexa Fluor® 750 replacement) 100 tests
產(chǎn)品貨號(hào)：eBioscience 47-1979-42
產(chǎn)品規(guī)格：100 tests
Anti-Human CD197 (CCR7) APC-eFluor® 780
Also known as: EBI-1, MIP-3 beta Receptor
Clone: 3D12
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 47-1979
Cat. No. Size
47-1979-41 25 tests
47-1979-42 100 tests
Description: The 3D12 monoclonal antibody reacts with human CCR7, also known as EBI-1 and CD197. CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naïve from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC’s. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation. Expression of CCR7 on the cell surface can be down regulated upon ligand binding.
