產(chǎn)品名稱：Anti-Mouse CD278 (ICOS) PerCP-eFluor® 710 (15F9) 100 ug 產(chǎn)品貨號：eBioscience 46-9940-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse CD278 (ICOS) PerCP-eFluor® 710 Clone: 15F9 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-9940 Cat. No. Size 46-9940-80 25 ug 46-9940-82 100 ug Description: The 15F9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. IOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells. The 15F9 antibody is reported to have functional activity.
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