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Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) **

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產(chǎn)品名稱: Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) **
產(chǎn)品型號(hào): 46-5975-82
產(chǎn)品展商: 其他品牌
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Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) **


Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) **  的詳細(xì)介紹
Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) **

產(chǎn)品名稱:Anti-Mouse Clec9A PerCP-eFluor® 710 (42D2) 100 ug
產(chǎn)品貨號(hào):eBioscience 46-5975-82
產(chǎn)品規(guī)格:100 ug
Anti-Mouse Clec9A PerCP-eFluor® 710
Also known as: DNGR1
Clone: 42D2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-5975
Cat. No. Size
46-5975-80  25 ug 
46-5975-82  100 ug 
Description: This 42D2 monoclonal antibody reacts with mouse Clec9A, which is also known as DNGR-1. Clec9A is a C-type lectin-like receptor expressed on conventional and plasmacytoid dendritic cells (DCs). In particular, CD8+ conventional DCs in the thymus, spleen, and lymph nodes, as well as CD24+ DCs in the blood, express Clec9A. This receptor is not detectable on most B cells, T and NK cells, monocytes, and macrophages. The cytoplasmic domain of Clec9A contains an ITAM motif that has been demonstrated to phosphorylate Syk tyrosine kinase, leading to NFAT activation. This signaling reportedly mediates the presentation of necrotic cell-associated antigens by CD8+ DCs in innate immunity.

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