產(chǎn)品名稱：Anti-Human CD85k (ILT3) PerCP-eFluor® 710 (ZM4.1) 100 tests
產(chǎn)品貨號：eBioscience 46-5139-42
產(chǎn)品規(guī)格：100 tests
Anti-Human CD85k (ILT3) PerCP-eFluor® 710
Also known as: LIR5, LILRB4, HM18, GM 4d
Clone: ZM4.1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-5139
Cat. No. Size
46-5139-41  25 tests 
46-5139-42  100 tests 
Description: The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.

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