產(chǎn)品名稱：Anti-Human/Mouse CD325 (N-Cadherin) PerCP-eFluor® 710 (8C11) 100 tests 產(chǎn)品貨號：eBioscience 46-3259-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD325 (N-Cadherin) PerCP-eFluor® 710 Also known as: neural cadherin Clone: 8C11 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-3259 Cat. No. Size 46-3259-41 25 tests 46-3259-42 100 tests Description: The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells.
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