產(chǎn)品名稱：PerCP-e710 Mouse PDCA-1 (clone ebio927), 100 ug 產(chǎn)品貨號：eBioscience 46-3172-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse CD317 (BST2, PDCA-1) PerCP-eFluor® 710 Also known as: plasmacytoid DC Ag-1, pDC Ag-1, BST 2, PDCA1 Clone: eBio927 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-3172 Cat. No. Size 46-3172-80 25 ug 46-3172-82 100 ug Description: The eBio927 monoclonal antibody reacts with PDCA-1 (BST2, CD317), a specific marker of plasmacytoid dendritic cells (pDC), also known as type I IFN-producing cells (IPC) in the naïve mouse. Mouse IPCs are typically CD11c+, CD11b-, B220+, Ly-6C+, and CD62L+. PDCA-1 is predominantly expressed by IPCs in the naïve mouse which represents a very minor population (<0.5%) of splenocytes. It is upregulated on numerous cell types following stimulation which triggers an IFN response. PDCA-1 cycles between cell surface and intracellular compartments and may function to regulate trafficking of secreted cytokines. PDCA-1 (BST2) is the protein recognized by antibody 120G8. The eBio927 monoclonal antibody has also been shown to have functional activity. The epitope recognized by eBio927 is distinct from eBio129c; thus, the antibodies can be used to costain, purify and identify pDCs.
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