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Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) **

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產(chǎn)品名稱: Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) **
產(chǎn)品型號: 46-1629-42
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Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) **


Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) **  的詳細(xì)介紹
Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) **

產(chǎn)品名稱:Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710 (FLEG) 100 tests
產(chǎn)品貨號:eBioscience 46-1629-42
產(chǎn)品規(guī)格:100 tests
Anti-Human CD162 (PSGL-1) PerCP-eFluor® 710
Clone: FLEG
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-1629
Cat. No. Size
46-1629-41  25 tests 
46-1629-42  100 tests 
Description: This FLEG monoclonal antibody recognizes human CD162, which is also known as P-selectin glyocoprotein ligand-1 (PSGL-1). This 120-kDa protein exists as a homodimer on the surface of monocytes, neutrophils, granulocytes, peripheral T cells, some B cells, and a subset of CD34+ hematopoietic progenitor cells (HPCs) in the bone marrow. CD162 binds CD62P (P-selectin), CD62E (E-selectin), and CD62L (L-selectin) to mediate leukocyte interactions with each other as well as with activated platelets and endothelium. Thus, CD162 plays a critical role in leukocyte adhesion and rolling. Furthermore, the binding of CD162 to P-selectin on HPCs has been demonstrated to inhibit hematopoiesis. Studies have also demonstrated CD162 as the receptor for enterovirus 71.

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