產品名稱：Anti-Mouse CD144 (VE-Cadherin) (clone BV13) PerCP-eFluor® 710, 100 ug 產品貨號：eBioscience 46-1441-82 產品規(guī)格：100 ug Anti-Mouse CD144 (VE-Cadherin) PerCP-eFluor® 710 Also known as: Cdh5, Cadherin-5, Vascular endothelial cadherin Clone: eBioBV13 (BV13) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-1441 Cat. No. Size 46-1441-80 25 ug 46-1441-82 100 ug Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
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