產(chǎn)品名稱：PerCP-e710 Human CD10 (clone eBioSN5c), 100 tests 產(chǎn)品貨號：eBioscience 46-0108-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD10 PerCP-eFluor® 710 Also known as: Common Acute Lymphocytic Leukemia antigen, Neprilysin, CALLA, NEP, Mme Clone: SN5c RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-0108 Cat. No. Size 46-0108-41 25 tests 46-0108-42 100 tests Description: The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c see different epitopes due to their ability to co-stain.
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