產(chǎn)品名稱(chēng)：Anti-Human CD1d PerCP-eFluor® 710 (51.1) 100 tests 產(chǎn)品貨號(hào)：eBioscience 46-0016-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD1d PerCP-eFluor® 710 Also known as: R3, R3G1 Clone: 51.1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-0016 Cat. No. Size 46-0016-41 25 tests 46-0016-42 100 tests Description: The monoclonal antibody 51.1 reacts with human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.
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