產(chǎn)品名稱：Anti-Human ILT7 CD85g PerCP-Cy5.5 (17G10.2) 100 tests 產(chǎn)品貨號(hào)：eBioscience 45-5179-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD85g (ILT7) PerCP-Cy5.5 Also known as: ILT-7, LILRA4 Clone: eBio17G10.2 (17G10.2) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 45-5179 Cat. No. Size 45-5179-42 100 tests Description: The eBio17G10.2 monoclonal antibody reacts with human immunoglobulin-like transcript 7 (ILT7), also known as CD85g. ILT7 is part of the leukocyte immunoglobulin-like receptor (LIR) gene family and associates with FcεR1γ to form a functional complex which transduces ITAM-mediated signals that negatively modulates TLR-induced type I IFN production by human plasmacytoid dendritic cells. ILT7 is expressed exclusively on plasmacytoid dendritic cells and is absent in monocyte derived DCs. Treatment with IL-3 or CpG causes a decrease in expression. Double staining of human PBMCs with eBio17G10.2 and anti-pDC marker BDCA2 yields virtually complete co-staining. Cross linking of ILT7 with eBio17G10.2 antibody causes reduced transcription of IFN-α1, IFN-α2, IFN-α4 and IFN-β.
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