產(chǎn)品名稱：Recombinant Human IL-12 p70 500 ug 產(chǎn)品貨號：eBioscience 34-8129-85 產(chǎn)品規(guī)格：500 ug Human IL-12 p70 Recombinant Protein Carrier-Free Also known as: Interleukin-12, IL12, p70 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 34-8129 Cat. No. Size 34-8129-82 100 ug 34-8129-85 500 ug Description: Interleukin-12 (IL-12) is a heterodimeric 70 kD (p70) cytokine composed of two covalently linked, glycosylated chains, 40kD (p40) and 35-kD (p35). IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells. IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-γ) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells. It is now established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-γ and IL-2 production. These cytokines can in turn promote T-cell responses and macrophage activation.
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