Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7,**
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產(chǎn)品名稱: Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7,**
產(chǎn)品型號(hào): 25-9829-42
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Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7,**
Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7,**
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Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7,**
產(chǎn)品名稱：Anti-Human LAP (Latency Associated Peptide) (clone FNLAP) PE-Cy7, 100 tests
產(chǎn)品貨號(hào)：eBioscience 25-9829-42
產(chǎn)品規(guī)格：100 tests
Anti-Human LAP (Latency Associated Peptide) PE-Cy7
Also known as: Pro-TGF beta 1, LAP/TGF beta 1
Clone: FNLAP
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 25-9829
Cat. No. Size
25-9829-41 25 tests
25-9829-42 100 tests
Description: The FNLAP monoclonal antibody reacts with human latency associated peptide (LAP, pro-TGF beta 1, LAP/TGF beta 1). Many different cells produce TGF beta and it mediates effects on the proliferation, differentiation and function of many cell types. TGF beta is synthesized as a precursor that contains LAP at the N-terminus and mature TGF beta at the C-terminus. Processing and cleavage of the precursor protein between amino acids 278 and 279 results in the formation of LAP dimers and TGF beta dimers that then non-covalently associate with each other to form the small latent TGF beta complex. LAP is secreted and can be found in the extracellular matrix. In addition, LAP can also be expressed on platelets and activated regulatory T cells. It is believed that this surface-expressed LAP is due to the binding of LAP to GARP (LRRC32), which is a transmembrane protein that is also found at high levels on platelets and activated regulatory T cells.
