產(chǎn)品名稱：eZFluor® 2-Color Cocktail - Human: CD3-FITC/CD8a-PE 50 tests 產(chǎn)品貨號(hào)：eBioscience 22-0308-72 產(chǎn)品規(guī)格：50 test eZFluor™ Anti-Human CD3 FITC and CD8 PE Cocktail Also known as: CD3 (UCHT1); CD8 (RPA-T8) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 22-0308 Cat. No. Size 22-0308-72 50 tests Description: This product consists of two fluorochrome-conjugated monoclonal antibodies to distinguish human peripheral CD3+ and CD8a+ T cells. The UCHT1 monoclonal antibody (mouse IgG1, κ) reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits γ and δ, the ε chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. The RPA-T8 monoclonal antibody (mouse IgG1, κ) reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8b chain (CD8αβ) or as a homodimer (CD8αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.
滬公網(wǎng)安備 31011002002623號(hào)
