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產(chǎn)品名稱:Anti-Human PD-1 (CD279) APC (MIH4) 100 tests
產(chǎn)品貨號(hào):eBioscience 17-9969-42
產(chǎn)品規(guī)格:100 tests
Anti-Human CD279 (PD-1) APC
Also known as: PD1
Clone: MIH4
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-9969
Cat. No. Size
17-9969-41 25 tests
17-9969-42 100 tests
Description: The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.