產(chǎn)品名稱：Human TRA-1-81 APC (Clone: TRA-1-81) 100 tests 產(chǎn)品貨號：eBioscience 17-8883-42 產(chǎn)品規(guī)格：100 tests Anti-Human TRA-1-81 (Podocalyxin) APC Also known as: TRA1-81, podocalyxin Clone: TRA-1-81 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-8883 Cat. No. Size 17-8883-41 25 tests 17-8883-42 100 tests Description: The TRA-1-81 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embyronal carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-81 antibody is lost upon cell differentiation. The TRA-1-81 epitope is resistant to neuraminidase digestion, unlike the epitope recognized by the related TRA-1-60 antibody. The TRA-1-81 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.
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